Diabetic gastroparesis is a condition that causes the stomach to not empty normally. It occurs in people with type 1 or 2 diabetes who experience damage to the vagus nerve. The vagus nerve helps your stomach muscles move food through the stomach and into the digestive tract. Once the vagus nerve is damaged, it can cause stomach discomfort, severe nausea, or vomiting after eating. These symptoms can be hard to manage and lead to other complications.
Although a medication (domperidone) to treat diabetic gastroparesis is used in many countries, it is not approved in the United States because it has been associated with serious side effects but can be used under a special agreement between a physician and the Food and Drug Administration. The study medication (deudomperidone) is expected to have similar benefits with fewer side effects. What we learn from the envision 3D study may help researchers learn more about a potential new option for people with diabetic gastroparesis.
Other common terms for gastroparesis are: